Doxidyl (deracoxib) is a popular NSAID drug for dogs commonly used to treat and control pain and inflammation caused by osteoarthritis and postoperative orthopedic and dental surgeries.
Around the world, veterinarians prescribe deracoxib as a pain reliever for canines, and it has proven results to help dogs in controlling pain and keep the pet calm.
In canines, Doxidyl™ works by inhibiting and limiting the production of the enzymes responsible for causing inflammation.
Before administrating this, every pet owner must know about the safe dosage of Doxidyl, its uses, safety precautions, side effects and safety tips for administering.
This blog article is an ultimate guide about Doxidyl™ (deracoxib) for dogs, including a dose calculator.

Doxidyl Dosage For Dogs

The recommended deracoxib Doxidyl dosage for dogs osteoarthritis and postoperative dental pain and inflammation is 1 to 2 mg/kg (0.45-0.91 mg/lb) once daily. For postoperative orthopedic pain and inflammation, the ideal deracoxib dose is 3-4 mg/kg (1.4-1.8 mg/lb) once daily.
Puppies Weight less then 5 kg or age less then four months should not take deracoxib with out vet prescription.
Doxidyl Dosage Chart For Dogs By Weight
Kg Dog Body Weight | Dog Weight lbs | Doxidyl Dosage For osteoarthritis & postoperative dental pain | Doxidyl Dosage For postoperative orthopedic pain |
---|---|---|---|
5 kg | 11 lbs | 5-10 mg | 15-20 mg |
10 kg | 22 lbs | 10-20 mg | 30-40 mg |
15 kg | 33 lbs | 15-30 mg | 45-60 mg |
20 kg | 44 lbs | 20-40 mg | 60-80 mg |
25 kg | 55 lbs | 25-50 mg | 75-100 mg |
30 kg | 66 lbs | 30-60 mg | 90-120 mg |
35 kg | 77 lbs | 35-70 mg | 105-140 mg |
40 kg | 88 lbs | 40-80 mg | 120-160 mg |
45 kg | 99 lbs | 45-90 mg | 135-180 mg |
50 kg | 110 lbs | 50-100 mg | 150-200 mg |
For safety purposes, always use the low dose and only increase the dose with your veterinarian’s advice.
Doxidyl 12mg, 25mg, 75mg,100mg Dosage Chart
Dog Weight | Doxidyl 12mg | Doxidyl 25mg | Doxidyl 75mg | Doxidyl 100mg |
---|---|---|---|---|
5 kg | 1/2 Tablet | * | * | * |
10 kg | 1 Tablet | 1/2 Tablet | * | * |
15 kg | 1, 1/2 Tablets | 1/2 Tablet | * | * |
20 kg | 1, 1/2 Tablets | 1 Tablet | * | * |
25 kg | 2 Tablets | 1 Tablet | * | * |
30 kg | 2, 1/2 Tablets | 1 Tablet | 1/2 Tablet | * |
35 kg | 3 Tablets | 1,1/2 Tablet | 1/2 Tablet | * |
40 kg | * | 2 Tablets | 1/2 Tablet | * |
45 kg | * | 2 Tablets | 1/2 Tablet | * |
50 kg | * | 2 Tablets | 1 Tablet | 1/2 Tablet |
The above Doxidyl 12mg, 25mg, 75mg, and 100mg dosage chart is only to be followed for osteoarthritis and postoperative dental pain and inflammation.
For the treatment of postoperative orthopedic pain and inflammation, follow the chart before this one.
Dose Calculator
Which Dogs Should Not Take Doxidyl (deracoxib)?
Doxidyl (deracoxib) is not safe for all dogs. Canines suffering from liver or kidney problems or having hypersensitivity to NSAIDs should not take Doxidyl until a veterinarian advises it.
The use of deracoxib for pregnant, nursing and puppies younger than four months of age has not been tested.
Make sure to take a vet’s advice for using the treatment.
Side Effects
The commonly reported side effects of Doxidyl in dogs are:
- Gastrointestinal ulceration
- Gastrointestinal Upset
- Vomiting & Diarrhea
- Liver and kidneys issues
- Mouth Foaming
Which Drugs are not to be used with Doxidyl?
Do give your pet Doxidyl parallel with NSAIDs or Pain relievers to avoid the risk of overdosing.
Safety Precaution

- Make sure to consult your veterinarian before giving your puppy any medicine.
- Make sure to administer a safe dose of the drug and avoid overdosing.
- Always choose the right tablets (mg) according to your puppy’s body weight, and avoid breaking the tablets more than half to avoid any overdosing effect.
- Doxidyl is not for use in humans and cats. Limit the drug to your dog only.
- Keep a close eye on your pet after administering the drug to your pet and contact your veterinarian if you observe any adverse effects.
- If you are using any other treatment for your pet or your pet has any illness history make sure to discuss it with your vet.
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