A Comprehensive Guide About Pyrantel Pamoate For Dogs

Dogs are susceptible to various parasites, including roundworms, tapeworms, and Giardia. While some of these parasites can be treated with over-the-counter medications, others may require more aggressive treatment from a veterinarian.

Pyrantel Pamoate For Dogs popular brand name Nemex® is an over-the-counter medication used to treat dogs for certain types of worms, including ascarid and hookworm infections.

Pyrantel pamoate (Nemex-2) Suspension is the best choice for eliminating nematodes from dogs.

It is essential to understand when Pyrantel is effective, what is the safe dosage of Pyrantel for dogs, and its benefits and side effects.

Pyrantel for dogs

Is Pyrantel safe for dogs?

Yes, Pyrantel is an FDA-approved safe dewormer medication for dogs that can be used to treat roundworms and hookworms in canines. It can be purchased over the counter and does not require a prescription.

Pyrantel is a depolarizing, neuromuscular-blocking agent that works by causing paralysis of the worms, which allows them to be passed through the dog’s digestive system.

Pyrantel pamoate is an effective dewormer for canines and puppies. It is safe for use in pregnant and lactating bitches, as well as in adult dogs.

Pyrantel Pamoate for dogs Dosage

The safe dosage of pyrantel pamoate for dogs is 1 ml/kg or (0.5 ml/lb) single dose. Each mL of Nemex®-2 contains 4.54 mg of pyrantel. For long treatment, this is recommended to use the medicine for treating puppies at 2, 3, 4, 6, 8, and 10 weeks of age. Lactating canines should be treated 2–3 weeks after whelping.

To treat T. canis reinfestation in Adult dogs mainly exposed to the infestation or live in heavily contaminated quarters may be treated at monthly intervals to prevent re-infestation.

Pyrantel Pamoate Dosage Chart for dogs

Dog weight kgDog weight lbsPyrantel Pamoate Dosage
1 ml/kg or (0.5 ml/lb)
1 kg2 lbs1 ml
2 kg4 lbs2 ml
5 kg11 lbs 5 ml
10 kg22 lbs10 ml
15 kg33 lbs15 ml
20 kg44 lbs20 ml
30 kg66 lbs30 ml
40 kg88 lbs40 ml
50 kg110 lbs50 ml

The above Pyrantel dosage chart for dogs is based on the Nemex®-2. If you are using a different brand, make sure to see the label of instruction carefully. 

Uses of pyrantel pamoate in dogs

In dogs, pyrantel removes large roundworms (Toxocara canis and Toxascaris leonina), hookworms (Ancylostoma caninum and Uncinaria stenocephala), and also be used to prevent reinfestation of T. canis in canines and lactating bitches after whelping.

Pyrantel Pamoate Suspension For Dogs

50 mg pyrantel pamoate suspension Contains 50 mg Pyrantel Pamoate per ml mean each 5 ml approximate 1 teaspoon contains 250mg Pyrantel Pamoate.

Remember that puppies weights less than 10 kg should take the 50mg Pyrantel Pamoate with the veterinarian’s advice only. 

Pyrantel Pamoate Suspension Dosage Chart For Dogs

Dog Weight in kgDog Weight in lbs50 mg Pyrantel Pamoate suspension Dosage
11-16 kg25-37 lbs125 mg (1/2 Teaspoon)
17-28 kg38-62 lbs250 mg (1Teaspoon)
29-39 kg63-87 lbs375 mg (1 ½ Teaspoon)
40-50 kg88-112 lbs500 mg (2 Teaspoon)
51-62 kg113-137 lbs625 mg ( 2 ½ Teaspoon)
63-73 kg138-162 lbs750 mg ( 3 Teaspoon)
74-84 kg163-187 lbs875 mg ( 3 ½ Teaspoon)
85 & Above188 & Above1000 mg ( 4 Teaspoon)

Side Effects 

Common side effects of pyrantel pamoate in dogs are vomiting and diarrhea. Less common side effects include lethargy, lack of appetite, and bloating. 

In rare cases, pyrantel pamoate can cause an allergic reaction in dogs. Signs of an allergic reaction include itching, swelling, and difficulty breathing. 

If you are concerned about giving your pet pyrantel pamoate, speak with your veterinarian.

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Which dogs should not take pyrantel pamoate?

Usually, pyrantel pamoate is safe and effective for dogs; however, some pets should not take medicine until their veterinarian advises it.

Dogs allergic to the medicine or weak and frail should not take pyrantel pamoate. Canines having kidneys and liver issues should also take medicine with the vet’s advice only.

How to give pyrantel pamoate to dogs? 

  • 1. Give the pyrantel pamoate as directed by your veterinarian.
  • 2. Be sure to follow the instructions on the label carefully.
  • 3. Pyrantel pamoate can be given with or without food.
  • 4. Give the medicine directly to your dog, rather than hiding it in food.
  • 5. If you are using the liquid form of pyrantel pamoate, shake the bottle well before each use.
  • 6. Give the medicine at regular intervals as prescribed by your veterinarian.
  • 7. Do not skip doses or stop giving the medicine early unless directed by your veterinarian.
  • 8. Finish all of the medicine as prescribed, even if your dog seems to be feeling better.
  • 9. Contact your veterinarian if you have any questions or concerns about giving pyrantel pamoate to your dog.

Can you overdose a dog on pyrantel pamoate?

No, you cannot overdose a dog on pyrantel pamoate. Overdosing is toxic and can cause serious health problems. Always make sure to follow the recommended dosage on the package.

Call your veterinarian immediately if you think your dog has ingested too much.

What are the symptoms of dogs having worms? 

  • 1. Dogs may have a pot-bellied appearance.
  • 2. The dog may have diarrhea or oily stools.
  • 3. There may be blood in the stool.
  • 4. Worms may be visible in the dog’s feces.
  • 5. The dog may vomit up worms.
  • 6. The dog may have a poor appetite.
  • 7. The dog may seem tired and listless.
  • 8. The dog’s coat may be dry and dull.
  • 9. The dog may scratch a lot.
  • 10. There may be worms in the dog’s vomit and poo


How often should you deworm your dog?

Most experts recommend deworming your dog every 3 months or at least once a year – preferably in the spring or fall. Some dogs may need to be dewormed more frequently if they are at higher risk for parasites, such as those who hunt or live in kennels. 

How long does pyrantel take to work?

Pyrantel begins to work against hookworms and roundworms within 24 hours, but you can see the complete treatment effect within 48-72 hours.

Can pyrantel cause diarrhea in dogs?

Pyrantel is an oral medication used to treat parasitic infections in dogs. It is effective against hookworms and roundworms.

Pyrantel may cause diarrhea in some dogs, which is usually mild and temporary. If your dog experiences severe or persistent diarrhea, contact your veterinarian.

How long after deworming will my dog pass worms?

It can take a few days to a week for your dog to pass all the worms after deworming. Some types of worms may be passed in a single day, while others may take several weeks.

Your veterinarian can advise you on the specific type of worms your dog has, the Best treatment medicine and how long it will take for them to be passed.

Can I touch my puppy if he has worms?

Yes, you can touch your puppy having worms. However, you should wash your hands thoroughly afterwards to prevent the spread of the parasites.

It is not possible for the parasite to be spread directly from dogs to humans. However, if the worm eggs are present in the environment (such as in soil or on contaminated surfaces), they can be transmitted to humans. This is why it is important to practice good hygiene when handling puppies or cleaning up after them




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