Marbofloxacin Brand name Zeniquin® is a veterinary fluoroquinolone antibiotic medication used to treat canine infections susceptible to marbofloxacin such as skin, soft-tissue infections, and urinary tract infections in dogs.
The use of Zeniquin for canines is both on-label and off-label. Federal law prohibits the extra-label use of this drug in food-producing animals.
Compared to other Veternaray fluoroquinolones medications, Zeniquin Marbofloxacin has the highest known tissue concentrations in the skin, kidney and lungs.
So Knowledge about the safe dosage of the medicine is essential to avoid any toxic effects or complications.
This blog post is a comprehensive article about Zeniquin (Marbofloxacin) For dogs. We will explore the benefits and side effects of using Deniliquin for dogs and safe dosage recommendations.
Dogs Escort Disclaimer: Zeniquin is a prescription medicine and only be used with a veterinarian’s advice. Self-medication can be harmful. This blog post guides dog owners about the medicine and will never replace your veterinarian advice.
Uses of Zeniquin® In dogs
The FDA has approved Zeniquin for use in dogs to treat skin infections, soft-tissue infections, and urinary tract infections.
Marbofloxacin is also effective in the treatment of canine leishmaniasis.
Zeniquin is also commonly used off-label to treat other bacterial infections in dogs, such as respiratory tract infections, gastrointestinal infections, and ear infections.
Make sure to inform your vet about the previous health history of your pet, if any, such as liver or kidney issues, seizures or other allergic problems.
Also, let your veterinarian know if your canine is on other medications.
Zeniquin Dosage For Dogs
The safe dosage of Zeniquin for dogs is 2-5 mg/kg or 1.25-2.5 mg/lbs once daily. Marbofloxacin should be administered for at least 30-33 days to treat skin and soft tissue infections. For treating UTIs, the recommended duration is 10-15 days.
The dose of any medicine or remedy depends on various factors, including body weight, age, the severity of the issue and the pet’s overall health condition. So your vet can decrease or increase the dose accordingly.
Zeniquin Marbofloxacin Dosage Chart for Dogs
| Canine Body Weight in Kg (2-5 mg/kg) | Canine Weight in lbs (1.25-2.5 mg/lbs) | Zeniquin (Marbofloxacin) Dosage (Once Daily) |
|---|---|---|
| 5 kg | 11 lbs | 10 mg |
| 8 kg | 17 lbs | 16 mg |
| 12 kg | 26 lbs | 24 mg |
| 15 kg | 33 lbs | 30 mg |
| 20 kg | 44 lbs | 40 mg |
| 25 kg | 55 lbs | 50 mg |
| 30 kg | 66 lbs | 60 mg |
| 35 kg | 77 lbs | 70 mg |
| 40 kg | 88 lbs | 80 mg |
| 50 kg | 99 lbs | 100 mg |
| 55 kg | 121 lbs | 110 mg |
| 60 kg | 132 lbs | 120 mg |
| Dog Weight #Kg | Zeniquin 25mg Tablets for dogs |
|---|---|
| 5 kg | ½ Tablet |
| 8 kg | 1 Tablet |
| 12 kg | 1 Tablet |
| 15 kg | 1, ½ Tablets |
| 20 kg | 2 Tablets |
| 25 kg | 2 Tablets |
| 30 kg | 2, ½ Tablets |
| 35 kg | 3 Tablets |
| 40 kg | 3 Tablets |
Zeniquin 25mg is recommended for dogs weight 5kg to 20 kg.
| Body Weight in Kg | Zeniquin 50mg for dogs |
|---|---|
| 15 kg | ½ Tablet |
| 20 kg | 1 Tablet |
| 25 kg | 1 Tablet |
| 30 kg | 1 Tablet |
| 35 kg | 1, ½ Tablets |
| 40 kg | 1, ½ Tablets |
| 50 kg | 2 Tablets |
| 55 kg | 2 Tablets |
| 60 kg | 2 Tablets |
If your pet’s body weight is 20-40 kg, it is best to choose Zeniquin 50mg for easy administration.
| Canine Weight in Kg | Zeniquin100mg for dogs |
|---|---|
| 35 kg | ½ Tablet |
| 40 kg | ½ Tablet |
| 50 kg | 1 Tablet |
| 55 kg | 1 Tablet |
| 60 kg | 1, ¼ Tablets |
| 70 kg | 1, ½ Tablets |
| 80 kg | 1, ½ Tablets |
| 90 kg | 2 Tablets |
Zeniquin 100mg is the best option for easy administration if you have an adult pet or a Giant breed.
How to Give Marbofloxacin to your dog?
- Marbofloxacin is a prescription medication and only be used with a veterinarian’s advice.
- Do Not Overdose. Continually administrate the safe dosage.
- If you are giving the liquid form, shake well before use.
- You can give the marbofloxacin tablets with or without food. Suppose your canine vomit while administrating without food. Give the next dose with the canine wet food.
- Food containing iron, calcium or aluminum should not be given parallel with marbofloxacin because these components can interfere with the absorption of medication, which may decrease the treatment bioavailability.
How long does it take for zeniquin to work?
Zeniquin usually takes 1-2 hours to work inside the body when administrated. However, improvement in the treatment will appear within 5 days, and you will gradually notice the healing process as treatment processes are completed.
What are the side effects of Marbofloxacin in dogs?
The most common side effects of Zeniquin in dogs are diarrhea, vomiting, and Allergic reactions (rashes, hives, facial swelling, Seizures, loss of appetite and weight loss.
When should I start giving Marbofloxacin to my dog?
Remember, Marbofloxacin can be toxic for dogs:
- Small and medium size puppies age less than 8 weeks.
- Medium size breeds age less than 12 weeks.
- Gaint breed age less than 18 weeks.
Only administrate Marbofloxacin to your pet when they pass the above age limit criteria.
Is Marbofloxacin Zeniquin safe for all dogs?
No, Marbofloxacin is not recommended for use in puppies less than 8 weeks old or pregnant or nursing dogs.
Canine Allergic to Marbofloxacin should take the medication only with the vet’s advice.
Marbofloxacin should also be used with caution in dogs with a history of seizures, as it can increase the risk of seizures.
What are the potential drug interactions of Marbofloxacin?
Marbofloxacin should not be used in dogs taking other medications that can cause QT prolongation, such as certain antiarrhythmics, antidepressants, and macrolide antibiotics.
Other medicines that can interact with Marbofloxacin are:
- Methotrexate
- Antacids
- Probenecid
- Sucralfate
- Nitrofurantoin
- Theophylline
- Cyclosporine
- Flunixin
- Warfarin
- Iron zinc
- Quinidine
Reference: https://www2.zoetisus.com/products/petcare/zeniquin
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